All for Joomla All for Webmasters

10 Healthy Fruits will Save You from Dangerous Diseases

Healthy FruitsHealthy Fruits have been recognized as a good source of vitamins and minerals and for their role in preventing vitamin C and vitamin A deficiency. People who eat best healthy fruit as part of a healthy diet in general reduced risk of chronic diseases. USDA MyPlate encourages you to make half of your plate of fruit and vegetables for a healthy diet.

Fruits are important sources of many nutrients, including potassium, fiber, vitamin C and folic acid (folic acid). Try to take blueberries, citrus fruits, blueberries or strawberries with phytochemicals that are being studied for additional health benefits.

The List of Best 10 Healthy Fruits:

1.Apple, 2. Strawberry, 3. Banana, 4. Mango, 5. Peach, 6. Berries, 7. Grape, 8. Watermelon, 9. Grapefruit, 10. Papya.

1. A Healthy Apple:

An apple a day holds a doctor, how many of you have heard this proverb in your life? The answer would probably be zero. However, if you think it’s just a proverb and there is no substance, you might be mistaken too. Apples are used safely in many forms: from pudding to vanilla to pudding, from juice to cake. However, there is hardly a better substitute than whole the best healthy fruits that can be beneficial in different ways. The apples are evenly crisp and juicy, they can be eaten whole and so you do not have to do anything to eat a fresh apple.

Prevention of Dementia

A study published in Journal of Food Science in 2008 suggested that eating apples can have benefits for your neurological health.

The researchers found that the inclusion of apples in their daily diet can cause neuronal cells against neurotoxicity caused by oxidative stress and can play an important role in reducing the hazard of neurodegenerative disorder because of that Alzheimer’s disease.

Stop all Types of Cancer

Scientists at the American Association for Cancer Research, among others, that consumption of flavonol-rich apple can help reduce the risk of developing pancreatic cancer by up to 23 percent. A researcher at Cornell University has recognized different compounds – triterpenoids – in apple dishes that have powered anti-enhancement actions versus cancer cells in the liver, colorectal and breast. Previous research has shown that whole apple extracts can reduce the number and size of mammary tumors in rats. Already, the US National Cancer Institute has consulted upper-level dietary fiber intake to minimize the hazard of colorectal cancer.

Reducing the Risk of Stroke

A study of 9208 men and women showed that those who ate more apples over a 28-year period had the lowest risk of stroke. The researchers concluded that apple intake is associated with a lower risk of thrombotic stroke.

Avoid Alzheimer’s Disease

A new study in mice shows that consuming apple juice can stop Alzheimer’s disease and combat the effects of aging on the brain. Study mice receiving an improved apple diet showed higher levels of acetylcholine neurotransmitter and improved in labyrinth tests than those of a regular diet.

In a study published in the journal Food Chemistry in 2014, a team of researchers studied how the bioactive compounds of seven different varieties of apples have good darn bacteria (Granny Smith, Brae burn, Fuji, Gala, Golden Delicious, McIntosh and Red Delicious) obese mice induced by the diet.

The researchers found that, compared to all other apple varieties, Granny Smiths seems to have the most beneficial effect on good intestinal bacteria. They suggest that their results may lead to strategies that prevent obesity and its associated disorders.

Getting a Healthier Heart

A thorough research associated absorption of highly soluble fibers with a slower accumulation of high-cholesterol plate in your arteries. The phenolic mix found in apple skins also save the cholesterol that thrusts your system from condenses in the nervous walls. When plaque forms in the arteries, it reduces blood flow to your heart, resulting in coronary heart disease.

2. Benefits of Strawberry:

This sweet fruit is heart-shaped with a taste of joy. The strawberry is not just food; it is a power supply because it is loaded with dozens of health benefits. Super highs are super-food packed with several essential vitamins and minerals with fat-free and fat-free cholesterol. Strawberry is such a healthy fruit that contains a lot of vitamins. The usual vitamins and amino acids present in these foods include vitamin A, C, K, etc., and tryptophan, threonine, lysine, cysteine, etc.

Strawberries Increase Immunity

“Strawberries are an excellent source of vitamin C,” says Madeleine Edwards, a registered nutrition consultant based in Toronto. Most mammals, other than humans, have the ability to produce vitamin C naturally, so it is so important to have their daily needs. “A portion of strawberries contains 51.5 mg of vitamin C, about half of its daily requirements,” says Edwards. “Double a serving to a cup and get 100 percent.” Vitamin C is a known immunity stimulant, as well as a powerful and rapid antioxidant. A 2010 UCLA study found that antioxidant power in strawberries would be “Bio-Available” or “ready to work in the blood” after eating fruit for only a few weeks.

Allergies and Asthma

Due to the anti-inflammatory effects of quercetin, eating strawberries can help alleviate the symptoms of allergies, including a runny nose, watery eyes, and food; So far, however, there have been no human studies to prove this theory.

Several studies have shown that the incidence of asthma is lower with a high intake of certain nutrients; vitamin C is at the top of the list.

Hair Moisturizer

Due to its antioxidant effects, the strawberry protects the membranes of the cells of the scalp and prevents the formation of a hydrophobic layer on the surface of the scalp, thus avoiding the isolation of the scalp. Combining egg yolk with strawberries is a great way to moisturize your hair.

Depression

Folic acid can also help with dejection by prohibiting over homocysteine in the body, which can confine blood and other nutrients from arriving the brain.

Excess homocysteine disrupts the production of wellness hormones, serotonin, dopamine, and norepinephrine, which regulate not only mood but also sleep and appetite.

Anti-Inflammatory Properties

The rich variety of antioxidants and phytochemicals of strawberries contributes to the fight against inflammatory diseases such as osteoarthritis, asthma, cancer, and atherosclerosis. According to the Harvard School of Public Health, strawberries can reduce blood C-reactive protein (CRP), which is responsible for inflammation. It was observed that women who had consumed 16 strawberries or more per week had a 14% lower risk of having high CRP levels. In my view, strawberry is the best nutritious fruits.

3. Banana for Health:

Bananas are grown in at least 107 countries and are among the world’s food crops in monetary value. Americans consume more bananas than apples and oranges combined. The agree that banana is the best fruits among healthy fruits.

With the world that consumes as many bananas, it is not surprising that people wonder: are bananas good? This article explores the potential health benefits of bananas, such as improving heart health and promoting regularity. It also examines the associated health risks.

Digestive Health

Mild foods such as applesauce and bananas are recommended for the treatment of diarrhea. They are part of an approach known as BRAT; this means bananas, rice, applesauce, and toast.

Electrolytes such as potassium are lost in large quantities during episodes of diarrhea and can make patients sick. Bananas can replace these lost nutrients. Bananas can also help promote regularity and replenish potassium reserves.

Bone Health

Bananas cannot be full of calcium, but they are still useful for keeping bones solid. According to a journal of the Journal of Physiology and Biochemistry of 2009, bananas contain a multitude of fructooligosaccharides. These are non-digestive carbohydrates that promote digestion probiotics and improve the body’s ability to absorb calcium.

Renewed Energy

Sports drinks, energy joints, and electrolytic gels are now very popular, but professional athletes are often seen eating bananas just before and even during their sport.

Watching tennis, for example, is not uncommon to see players eating a piece of banana between games. If a banana can contain a professional tennis player, it should be classified as a healthy energy source.

Banana is a Food Operation

Bananas are a sweet fruit, so eating too much and not maintaining good dental hygiene practices can result in tooth decay. They also do not contain enough fat or protein to be a healthy meal, or an effective snack after training.

Cure for Ulcers and Acid

Bananas are a well-known cure for heartburn. They help balance the pH of the stomach and improve the protective layer of mucus and relieve pain. The fiber content also transmits foods through your digestive system more quickly – preventing reflux.

Eating Bananas can help regularly protect against stomach ulcers. In the long term, bananas dilute the protective barrier of mucus in the stomach and prevent damage caused by hydrochloric acid. Bananas also contain protease inhibitors that help eliminate bacteria from the stomach that can cause gastric ulcers

4. Health Benefits of Mango:

Who doesn’t like mango? If I call a statistic I think 95% people will say mango is a super tasty and healthy fruit. Mango is rich in fiber, so if you have at least a daily handful in your diet, it is almost guaranteed to prevent constipation, piles, and symptoms of a spastic colon. Research and studies published in in-depth food science and food security surveys have shown that dietary fiber has a positive effect on the elimination of degenerative diseases, including some cancers and heart disease. Now you have even more reasons to include these delicious fruits in your daily diet.Ripe Mango

Promoting Sexual Health

Mangos are an excellent source of vitamin E. Although the popular link between sexual desire and vitamin E was originally created by misdirected generalization in rat studies, other studies have shown quantities balanced (shown in whole foods)

Adjust Blood Pressure

The Mangos have an impressive content of vitamins, which ensures overall health. They are rich in potassium (4% in 156 mg) and magnesium (2% in 9 mg) and mangoes are excellent natural remedies for patients with high blood pressure. They also contain selenium, calcium, iron, and phosphorus. They are believed to be the power of the vitamin because they are rich in riboflavin, vitamin B6, vitamin A, vitamin C, vitamin E, vitamin K, niacin, folate, thiamine and pantothenic acid. These components help you avoid a number of diseases that can result from deficiencies of these vitamins and minerals. Vitamin E content in mangoes can even help increase your sex life by activating the activity of your sex hormones.

Improve Digestion

Mango JuiceOne of the main reasons why mangoes are ideal for digestion is the presence of a fiber that prevents constipation. Fiber holds us so long (25). It keeps our colon clean and allows you to work optimally. In addition, mangoes contain certain digestive enzymes that decompose proteins and promote digestion.

Useful During Pregnancy

Mangoes are great healthy fruits for pregnant women and it is also very beneficial for a pregnant woman because iron requirements during pregnancy are extremely important. Doctors usually prescribe iron pills during pregnancy, but instead of supplements, you can enjoy a healthy iron-rich diet with juicy mangoes. The taste buds during pregnancy normally miss a little amount of their sensory, so that mangoes will expressly be the cheering of your day, for more than its health benefits.

Promoting Brain Health

Mangoes have abundant amounts of vitamin B6, which is essential for maintaining and improving brain function. These vitamins contribute to the fusion of large neurotransmitters, which helps in determining mood and changing sleep patterns. Of course, they provide significant amounts of this vitamin. Using the handles as part of your diet, you can be sure of a healthy brain and effective nervous functioning. They would also avoid medical supplements that contain a long list of possible side effects. The content of glutamic acid in mangoes also improves the concentration and power of your memory.

5. Peach for Health:

An average medium of fishing (147 grams) has 50 calories, 0.5 grams of fat, 0 grams of cholesterol and sodium, 15 grams of carbohydrates, 13 grams of sugar, 2 grams of fiber and 1 grams of protein. There are 6% of your daily vitamin A and 15% of your daily vitamin C needs. An average fishery also includes 2% or more of the daily value of vitamins E and K, niacin, folic acid, iron, choline, potassium, magnesium, phosphorus, manganese, zinc, and copper.Tree and Peach

Skin Disorders

The antioxidant of vitamin C, when eaten in its natural form (in whole foods like peaches) or applied topically, can reduce wrinkles, improve the overall texture of the skin and help fight the damage caused by the skin and the sun. Vitamin C also plays an important role in the formation of collagen, the system for transporting your skin.

Tissue Synthesis

Fresh peaches are a moderate source of antioxidants, vitamin C. Vitamin C has antioxidant activity and is necessary for the synthesis of connective tissue in the human body. The consumption of foods rich in vitamin C helps to maintain resistance to infectious agents and to eliminate harmful free radicals.

Control of High Cholesterol

Eating peaches on a regular basis can help high cholesterol levels and problems that lead to diabetes and heart disease. This is chiefly because of the reality that the peaches take on phenolic mixes that prevent the oxidation of low-density lipoproteins or LDL, cholesterol. In addition, foods rich in beta-carotene such as peaches are good for lowering cholesterol levels in the blood.

Improves Cardiovascular Health

Antioxidants in peaches benefit the heart by destroying free radicals that can cause chain reactions in your body and damage or kill cells. Peaches also contain bioactive compounds that help fight metabolic syndrome, a combination of risk factors that cause inflammation, obesity and heart problems.

There are also other nutrients in peaches that promote cardiovascular health by lowering cholesterol and increasing blood flow to the heart. Regular consumption of peaches helps protect you against heart attacks and strokes.

Detoxify Your System

One of the benefits of peaches is that they help remove toxins from your system. The high content of calcium and fiber reduces the risk of stomach ulcers, inflammation, and kidney disease. Peaches are also beneficial to cure digestive problems such as gastritis and colitis. In China, peach tea is used as a natural remedy for cleansing and detoxifying the kidneys. Peach can help eliminate worms from the stomach and cure discomfort from the stomach.

6. Nutrition of Berries:

What makes berries so special are their high levels of phytochemicals – natural nutrients that help protect cells from damage – says nutritionist Nancy Copperman, MS, RD, CDN, Director of Public Health Initiatives, Community Health on North Shore -Long Island Jewish Health System in Great Neck, NY So plug in blueberries, strawberries, raspberries and blackberries and start chewing.

Alzheimer’s disease and Resveratrol

The berries lead a process called neurogenesis or make new neurons, explains Shukitt-Hale. This can help our memories and our ability to learn. They also participate in brainwashing activities. They help to remove toxic proteins that accumulate in the brain, such as beta-tau and amyloid. Excessive amounts of these proteins are related to Alzheimer’s disease.

Blood Glucose Control

In particular, strawberries have been shown to reduce blood glucose and insulin levels after meals. Scientists believe that a key antioxidant in strawberries blocks the activity of an enzyme responsible for the breakdown of starch into simple sugars, which means that less simple sugars are released into the bloodstream, lowering blood sugar levels and a corresponding response to insulin. This is the key to weight control because insulin carries excessive sugars into fetal cells. Check out my taco strawberry and an avocado sandwich recipe for a new way to taste the healthy fruit.

Berries can Prevent Parkinson’s Disease

People who eat at least two servings of berries in the week are 25 percent less likely to develop Parkinson’s disease than their counterparts, according to the research, which was published in the journal Neurology. The same research showed that men with the best intake of flavonoids – abundant in berries – reduced their risk by 40 percent. In addition to eating them flat, you can also take your berry portions by adding fresh or frozen foods to other high-nutrition foods such as yogurt, oatmeal, and salads.

Metabolism Booster

It has been shown that raspberries contain a natural substance called ketones, which are similar to capsaicin, the compound that gives peppers their fire. Animal studies have shown that ketones with raspberries prevent an increase in body fat and visceral fat, deep internal fat as the most dangerous because of its relationship to an increased risk of heart disease, type diabetes 2 and certain types of cancer. I love raspberries as they are, but they are also awesome in the perfect, hot or cold cereals, or as topping for whole French toast.

Antioxidants

Berries are powerful sources of antioxidants, which act primarily as small lifeguards, which protect cells from damage that can lead to premature aging and disease. But antioxidants are also related to weight control. Some exciting new research from the University of Florida has revealed that people who consume more antioxidants weigh less, even if they do not eat fewer calories.

7. Grapes Healthy Benefits:

The combination of unique texture and sweet and sour taste makes grapes a very popular snack between meals, as well as a refreshing addition to fruit and vegetable salads.

The grapes are small round or oval berries, which have a semi-transparent meat surrounded by a soft skin. Some contain edible seeds while others are invisible. Like blueberries, grapes are often covered with a whitish protective flower. Grapes that are eaten as they are used or used in a recipe are called table grapes and unlike grapes (used in making wine) or raisins (used to make nuts).Grapes

 

Cardiovascular Benefits of Grapes

Nobody system is better placed to take advantage of the benefits of antioxidants and anti-inflammatory molecules in grapes than in the cardiovascular system. All cells in our blood need protection from possible damage to oxygen (especially in our arteries where the oxygen concentration in our blood is particularly high). Our blood vessel pads also need a strong antioxidant support. Chronic inflammation in our cardiovascular system is also a major concern for many types of cardiovascular disease, and optimal regulation of the activity of the inflammatory system is particularly important in reducing our risk of atherosclerosis and other conditions.

Full of Antioxidants

Where green grapes are really nutritious, it is in its antioxidant content. Antioxidants are the chemical “shields” of your body. They are responsible for the neutralization of highly reactive compounds that otherwise could be oxidized and damage essential structures such as DNA. Green grapes contain antioxidants called flavonols and have an antioxidant capacity in red grapes, according to a 2014 study published in “Antioxidants”.

Increased Brain Power

Studies have shown that resveratrol helps increase blood flow to the brain; therefore, could help speed up the mental responses and prove beneficial for those suffering from brain-related diseases such as Alzheimer’s. A study by the University of Switzerland also revealed that resveratrol can help eliminate plaques and free radicals that affect the brain.

Diabetic Neuropathy and Retinopathy

Some studies have shown that resveratrol can protect against diabetic neuropathy and retinopathy, the conditions caused by poorly controlled diabetes, where vision is severely affected. A study in which diabetic rats were treated with resveratrol for two weeks showed that the effects of neuronal changes and damage associated with diabetic neuropathy were reduced.

Cognitive Benefits of Grapes

Several recent studies on the consumption of grape extract by animals, as well as the supply of grape juice by people, suggest that grapes can provide us with important cognitive advantages. For example, daily Concord grape juice intake was shown in 1-2 cups over a period of several months to improve the number of subjects in the California Verbal Learning Test.

8. Why Need Watermelon?

Health benefits of watermelons include prevention of kidney disease, high blood pressure, cancer prevention, diabetes, heart disease, heat stroke, macular degeneration, and impotence.

The question is, why is there so much madness on watermelons? At first glance, it can only resemble a formidable water ball. We all know that there is nothing more refreshing than a big poop of iced watermelon on a hot summer day and has an elegant scientific name for Citrullus lanais, but what is the real reason why so many people go into shopping every summer, so a big buy awkward fruit? Well, it is difficult to reduce it to a single reason; there are many of them.Slice Watermelon

Skin Health

Watermelon is ideal for the skin because it contains vitamin A, a nutrient needed for the production of tallow, which helps keep your hair hydrated. You know that Vitamin A is also required for the enhancement of all body tissues, with along the skin and hair.

Proper consumption of vitamin C is also necessary for the construction and maintenance of collagen, which provides structure for the skin and hair. In addition, watermelons contribute to total hydration, which is crucial for healthy skin and hair.

Treats Kidney Disease

Watermelons contain a large amount of potassium, which is very useful in cleansing or washing toxic deposits in the kidney. In addition, it is useful to reduce the concentration of uric acid in the blood, which reduces the risk of kidney damage and the formation of kidney stones in this organ. In addition, with high water content, it causes frequent watering, which in turn is useful for cleansing the kidneys. In addition, antioxidants in watermelons ensure good kidney health for a long time and reduce the signs of premature aging such as wrinkles and age spots on the skin.

Reduces Body Fat

Citrulline in watermelons has reduced the build-up of fat in our fetal cells. Citrulline is an amino acid that is converted to arginine by means of the kidneys. When our bodies absorb citrulline, you can pass the conversion stage to arginine when required. Citrulline, when consumed, has the ability (through a series of steps) to block TNAP activity (non-tissue alkaline phosphatase), which will help our fat cells to create less fat and thus prevent an excessive accumulation of body fat.

Diabetes Control

Low-energy and low-sugar diabetic patients often complain about hunger because they do not eat their basic diets, which make them feel half-fed. Watermelons can be a good addition to them. Despite the cream in taste, a thick wedge gives you very few calories, since ninety-nine percent of your total weight consists of water and food. On the other hand, various vitamins and minerals such as potassium and magnesium contribute to the proper functioning of insulin in the body, which reduces the blood sugar level. Arginine, different element found in watermelons, is very useful in improving the outcomes of insulin on glucose. Diabetic patients can also use curry, steaks, and salads from the melon bark, which are even lower in sugar.

Improvement of Male Fertility

Zinc in watermelon seeds is important for the male reproductive system. According to a Chinese study, zinc supplementation can significantly improve sperm quality in infertile men (12). In addition, zinc is more than iron as the most abundant element in human tissues. And trace elements such as zinc play an important role in the male reproductive system because they have a high activity at the molecular level. Studies have also found lower levels of zinc in the seminal plasma of infertile men than in normal men. Although further studies are needed, the possibility is encouraging.

Watermelon seeds are also good sources of manganese. According to the University of Maryland Medical Center, low levels of manganese can also contribute to infertility.

9. Grapefruit Nutrition:

Grapefruit is not only a delicious and spicy fruit, consume what there are many health benefits. Not only is it low in calories and carbohydrates, but before eating can help you curb your appetite, which makes you less likely to eat a lot. In addition, it is highly soluble insoluble fibers, which will reduce blood sugar and promote regularity. In addition, grapefruit is rich in antioxidants and contains 77 mg of vitamin C per serving, which helps to support your health and immune system.Grapefruit

Grapefruit can Reduce Triglyceride Levels

There is another reason why grapefruit can be good for your heart: it reduces triglyceride levels. Triglycerides are another type of “bad” LDL cholesterol that can quickly clog the arteries.

The same study that found that adding a volume of grapefruit reduces cholesterol also revealed that these simple daily triglycerides have decreased by up to 27%. They were patients who already had coronary heart disease and therefore had a high risk of heart attacks and other complications. The red grapefruit especially surpassed its blond cousins by lowering triglycerides.

Liver Cleanser

This helps the liver by cleansing the unhealthy toxins from the body. Drinking or eating grapefruit leads to better feel. It is said that detoxification of the liver improves general help to alleviate the symptoms of chronic diseases such as depression, rigid muscles, and chronic headaches. Dangerous toxins that affect our health are around us, cleansing can help eliminate some of these deadly toxins.

Insulin Resistance

Grapefruit contains specialized antioxidants such as naringenin, which has improved insulin sensitivity and maintained a healthy weight. Scientists have found that Naringenin burns the liver to burn fat instead of storing it. Grapefruit has been shown to help reduce insulin levels, and it has been shown in one study that grapefruit was as good as metformin in reducing blood sugar levels with decreased fasting obesity in 13 %.

Prevention of Lung Cancer

Research shows that grapefruit is also a prevention and a fight against lung cancer. The consumption of three 6 ounce glasses per day has been shown to reverse the damage caused by cigarettes and cigarettes to smokers. Grapefruit activates enzymes that fight lethal diseases. Pink grapefruit has proven to be particularly effective in preventing lung cancer.

High Cholesterol

Due to the highly soluble fiber of pectin in grapefruit, this type of fiber is useful for removing cholesterol in the intestine. A study conducted at the Hebrew University of Jerusalem showed that eating 1 red grapefruit per day after 30 days reduced LDL cholesterol by 20.3%, a yellow grapefruit decreased by 10.7% without eating grapefruit. Triglycerides also shortened by 18.7% including red grapefruit, while it reduced by 7.2% for yellow grapefruit.

10. Papaya for Health:

What is your think papayas are not healthy fruits? You will be surprised to know about the health benefits of papaya. The health benefits of papaya include improved digestion, relief of a toothache, regulate menstruation, increased immunity, weight loss, skin care and promotes better heart health. Papaya is also known as Carica papaya, paw or papaya is believed to prevent cancer. It is not surprising that the fruit is very popular for its high nutrition and medicinal value.Ripe Papaya

Papaya Promotes Digestive Health

Nutrients in papaya have also been used for the prevention of colorectal cancer. Papaya fiber can bind to colon cancer toxins and release them from healthy intestinal cells. In addition, papaya folate, vitamin C, beta-carotene and vitamin E were associated with reduced risk of colorectal cancer.

These nutrients provide synergistic protection for intestinal cells to damage free radicals to their DNA. Increasing the intake of these nutrients for the enjoyment of papaya is a good idea, especially for people at risk for colon cancer.

Protects Against Arthritis

Arthritis can be a truly debilitating disease and people who have it can greatly reduce their quality of life. Eating Papayas are good for bones because they have anti-inflammatory properties as well as vitamin C, which help to maintain various forms of arthritis from a distance. A study published in the Rheumatic Disease Records showed that people who ate foods low in vitamin C were three times more likely to have arthritis than those who did not.

Improves Digestion

Slice PapayaIn modern times it is almost impossible to avoid eating foods that are bad for your digestive system. We often find ourselves with junk food or foods prepared in excessive amounts of oil. Taking a regular papaya can put these episodic oversights as it is a digestive enzyme informed as papaya with fiber that collaborations develop your digestive health.

Prostate Cancer

The antioxidant and the high content of papaya vitamins play an important role in the prevention of certain types of cancer. One study found that the combination of green tea and lycopene had an impact on the prevention of prostate cancer. 16 Papaya is rich in lycopene.

Reducing Stress

After working hard all day, it’s a good idea to go home in a bowl of papayas. The miracle fruit is rich in various nutrients such as vitamin C, which can keep you stress-free. According to a study by the University of Alabama, found that 200 mg of vitamin C can help regulate the flow of stress hormones in rats.

Leave a Reply